Spenolimycin, a new spectinomycin-type antibiotic. I. Discovery, taxonomy and fermentation.
نویسندگان
چکیده
Spenolimycin, a new spectinomycin-type antibiotic, was discovered in the fermentation broth of a new actinomycete named Streptomyces gilvospiralis sp. nov. strain AB634D-177. Although a small amount of spectinomycin is coproduced by strain AB634D-177, the culture is different from other known spectinomycin-producing actinomycetes. Spenolimycin was obtained by conventional submerged culture in 14-liter fermentors with a peak antibiotic titer of 140 micrograms/ml.
منابع مشابه
Spenolimycin, a new spectinomycin-type antibiotic. II. Isolation and structure determination.
A new water-soluble, basic antibiotic has been isolated from the fermentation beers of Streptomyces gilvospiralis sp. nov. The structure of the antibiotic has been deduced from spectral studies and confirmed by chemical degradation to spectinomycin. This structure, 3'-O-methylspectinomycin-3',4'-enol ether has led to the name spenolimycin.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 37 12 شماره
صفحات -
تاریخ انتشار 1984